BDBM397152 US10596172, Compound I-40::US10828300, Compound I-40::US11351168, Compound I-40::US9987276, Compound I-40

SMILES Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2CN(CCc2c1)C(=O)C=C

InChI Key InChIKey=AEDSWOUXTMUZJT-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 397152   

TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM397152(US10596172, Compound I-40 | US10828300, Compound I...)
Affinity DataIC50: <10nMAssay Description:BMX: The activity of selected compounds of this invention in the BMX inhibition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM397152(US10596172, Compound I-40 | US10828300, Compound I...)
Affinity DataIC50: <100nMAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM397152(US10596172, Compound I-40 | US10828300, Compound I...)
Affinity DataIC50: <10nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent